I have done 2x PBP's on tandems and am planning my third tandem PBP this year, its a good tandem ride, nice and rolling. We ride the first 150 Km in 03 as a six up, at 40+KPH but we were behind the Italian tandem - they would not hold any sort of steady pace line (italian driving) so we ended up doing two turns on the front. Expect to gain a shoal of wheel suckers behind you if you have any kind of speed - we got a whole gang of french and italians out to Brest in '03, then joined up with an American group on the way back who did some turns on the front. Steve still keeps in touch with one of them.
In 07 on the way back people were so tired that the could not take a tow even when offered, we rode back with Stue Lee on his trike - really good company - sat behind us on the flat and alongside for a chat on the climbs. riding a tandem makes fiends and often good ones.
And I was the one carrying the spare clutches in 03 and 07- that was because they failed for us on one of our '03 qualifiers, we cable tied the big sprocket to the spokes and rode 100 miles on a fixed tandem (with gears). They have now been re-designed with deeper sprags and nickel plating. Take any special parts if you can - the spare sprags could have been fitted in minutes. I would recommend a spare folding tyre and brake parts - all the workshops tend to be lightweight road bike biased.
If anyone want's some DT tandem hub spares PM me as the hub flange tore along the perforations last year - after only 18,000 miles
The biggest problem is the riders rear ends, less room for in saddle adjustments lead to more wear and tear. The rest is of course twice the fun!