In general, yes you can. But a couple of things to watch out for.
You are aiming for 1:1 pixel mapping.
That means that your PC sends an image which is for example 1920x1080 to a display which has a 1920x1080 native panel resolution, and no re-scaling nonsense is applied along the way.
1) Overscan. Kill it with fire. Some cheaper TVs have overscan that cannot be disabled. This means the computer's desktop will be stretched so that the edges of the desktop are off the visible screen area. This can be 'fixed' by scaling on the PC, but the double-scaling ( once in the PC, and once in the monitor doing the overscan ) results in a horrible blurred image. Disable overscan for the PC input. The menu items are often not clearly labelled, but may say things like 'PC mode' and 'Video Mode'.
2) Non-square pixels. Throw it in the bin. Computers expect the individual pixels to be square (1:1 aspect ratio). Some TVs are physically 16:9, but the number of pixels on the display panel are not. When crappy TVs with non-square pixels are displaying video from the TV at say 1920x1080 which is 16:9 on a panel who's native resolution is not 16:9, then the on-board re-scaler deals with it, and stretches and squeezes the image so it displays correctly on the screen which is physically 16:9 but pixel-wise is not. You will never get a satisfactory PC display from these horrors.