the purpose of spikes is widely misunderstood, and is in fact exactly the opposite to what most people assume.
Spikes are meant to
couple the speaker stand to the floor, so that (in stark contrast to a wobbly or perfectly elastic mounting) both it and the speaker cabinet are less likely to flap about in antiphase to the speaker diaphragm, which will colour and distort the sound.
[BTW vs (say) being sat on carpet, spikes have measurably reduced the vibrations in a speaker stand by a factor of 100].
However (esp on a suspended floor) you may also excite the floor, too, once it is coupled thus. So this again may distort the sound.
Usually the bass is noticeably different (usually better) when you have spikes into the floor.
A similar consideration applies to the mounting between the speaker stands and the speaker cabinets.
In all instances if the load is not evenly spread between four feet (e.g. because the surfaces are not perfectly flat) the speaker/speaker stand can wobble slightly and this will distort the sound.
Rubber mountings of any kind work in a different way; they more easily allow all four feet to share the load. If they have the right properties, they do also decouple the speaker from the speaker stand, the speaker stand from the floor etc. The idea here is that the unwanted antiphase vibrations are moderated by the damping qualities of the rubber; here the devil is in the detail, so not all such mountings work in the same way or as well as one another.
Probably the best way of stopping the antiphase vibrations at source is to make the speaker cabinet as massive as possible; this instantly reduces the capacity for the 'tail to wag the dog'. If you can do it, simply bolting a 1/2" slab of steel to the bottom of each speaker will help, (ideally with an intermediate layer of rubber so that the steel plate cannot 'ring' and colour the sound).
A reasonably well-informed piece to read is this one;
http://www.audioholics.com/loudspeaker-design/speaker-spikes-and-cones-2013-what2019s-the-pointBTW a simple axiom to follow is this; if you can't hear the difference, it probably doesn't matter.
cheers