The hospital where I worked (Carlisle) has a regular 24/7 van service to and from Newcastle. That’s because that was the nearest blood transfusion centre, as well as tertiary centre for everything else so a reliable transport service was essential. Also using contracted taxis if a van was not available. This has been the case for many years, long before blood bikers, out of necessity. In an urban setting, using bikes might have an advantage, getting through traffic more quickly, but in an rural setting, I don’t think they add much value, though they do operate in Cumbria also. But they are popular with the public, and don’t cost the NHS anything.