Dingle peninsular. Just utterly beautiful. Highly recommend it.
J
Seconded. My first wife was from Castlegregory. Dingle’s a bit touristy though.
Avoid the cliffs of Moher. Used (as in 35 years ago) to be fantastic, a half collapses car park and bits of cliff you could get right to the edge of. Now, “award winning” visitors centre, acres of coach parking, and all paths kept well back from the edge.
Do try the Burren. Magnificent limestone pavement, and a real sense of peace.
You could, if heading SE to (N)W go over the Military Road in Wicklow. And Glendalough is worth a visit.
The beaches of Clare are lovely and quiet, the scenery - a patchwork of tiny fields with 2m high stone walls built from the rocks cleared from the ground - fantastic.
The Midlands are extensive, flat and very boring.
I’d maybe try a route Rosslare, Wicklow, across to Kerry, head north to wherever, then back across and down.