I have 2 wheels, so I'm running one for turbo and one for outside. Both are double sided so that gives me options without having to remove cogs (though I guess that's non optimal aero). I will have to switch chains around as well though, because the turbo wheel needed a huge cog.
I was planning on starting out with 54x16, moving to 54x15 (near enough your 50x14) later in the year if form allows. The only TT I did on this bike last year was 52x16 because those were the only rings/cogs I had, but I should be much more aero this year.
I don't think I'll be doing 35mph - that's seriously impressive!
If I can do a 10 as fast as you do a 100 I'll be chuffed!