Author Topic: Lung Function Research - Call for volunteers  (Read 15703 times)

Lung Function Research - Call for volunteers
« on: 16 May, 2016, 04:32:03 pm »
Posting on behalf of a former AUK veteran's 'points champion'

Quote




Call for Volunteers from Audax Cyclists for Lung Function Research.

Audax cyclists previously volunteered so that the Guy’s Team could uncover a relationship between age, exercise and health.

As a result of your input ground breaking findings were published in the Journal of Physiology and gained world-wide publicity.

The Guy’s team are asking men and women aged fifty and over to please come forward again, in order to take part in a study on lung function.

The study will involve spending half a day at Kings College Denmark Hill undergoing testing. We are particularly interested in understanding the role the diaphragm exerts on neural respiratory drive and breathlessness. Ultimately these tests will give important information on breathlessness in disease.

You will be tested by doctors and technicians who are experts in respiratory physiology in order to ensure that the research is of the highest quality. There is very low risk involved especially for healthy cyclists. You will however be asked to swallow two thin tubes (smaller than the inside of a biro) so that the electrical activity of the diaphragm can be measured. These are routine medical tests and most of the testing team have undergone the procedure with little difficulty.

The Guy’s Team is initially looking for ten or twelve volunteers for these tests. Accepted volunteers will be given, in addition to the specific diaphragm test, a full lung function “MOT”.

Interested cyclists should please get in touch with Caroline at the email address below where greater detail of what to expect during your four hour visit to Guy’s will be given.

Professor Norman Lazarus

Email: caroline.jolley(at)kcl.ac.uk

Re: Lung Function Research - Call for volunteers
« Reply #1 on: 16 May, 2016, 06:35:54 pm »
So sad it's over fifties. I have bronchiectasis, but my FEV1 was 5.76 last time I had spirometry. I do use power breathe regularly.

Hopefully they'll have funding for more research when I'm 50.

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mmmmartin

  • BPB 1/1: PBP 0/1
    • FNRttC
Re: Lung Function Research - Call for volunteers
« Reply #2 on: 23 June, 2016, 11:02:42 pm »
This is worthwhile and she's looking for more volunteers. I did it today and it was an interesting experience. They are very friendly and helpful, and the one who took me through it was a Palestinian doing a medical training year in London funded by a charity. It was very interesting, talking about medical care in Gaza. "There is a lot of trauma care" she said.
I'd recommend auks help out.
They run a tube up your nose and into your windpipe to pick up the diaphram movements, and you breath in and out when told to. This is while seated, then you do a similar thing on a recumbent-type gym bike as they increase the load until you can't pedal against the weight against you.
All in all, I enjoyed it.
caroline.jolley@kcl.ac.uk
is the chief consultant's email. It's at King's, Denmark Hill. They pay your travel. It took me three hours.
I commend it to the house.
Besides, it wouldn't be audacious if success were guaranteed.

Assasin

  • It can only get better
Re: Lung Function Research - Call for volunteers
« Reply #3 on: 24 June, 2016, 08:35:33 am »
My debut there at kings 13:00 today.
Not looking forward to the sensor through your nose bit but interested to see what they do and how it all works.
Might even find out if i am fit enough to carry on riding !!

mmmmartin

  • BPB 1/1: PBP 0/1
    • FNRttC
Re: Lung Function Research - Call for volunteers
« Reply #4 on: 24 June, 2016, 09:57:40 pm »
how did it go?
Besides, it wouldn't be audacious if success were guaranteed.

Assasin

  • It can only get better
Re: Lung Function Research - Call for volunteers
« Reply #5 on: 26 June, 2016, 11:15:29 pm »
It waS fine.
I had the same crew as you did.
Don't have the full results as yet.
Cough was off the scale.
Lung capacity 5 litres.
Can't get out of breath - legs pack up first in anerobic zone at 275w output.

The optional 'magnetic' nerve stimulation for a max result was interesting.
Not sure how many volts it was......

Well worth the trip if you want a free lung MOT

mmmmartin

  • BPB 1/1: PBP 0/1
    • FNRttC
Re: Lung Function Research - Call for volunteers
« Reply #6 on: 27 June, 2016, 10:26:44 am »
interesting, i got to 200w and the sweat was pouring down my face. but i was still breathing fairly slowly. The medic from Palestine was interesting to talk to yes?
Besides, it wouldn't be audacious if success were guaranteed.

Assasin

  • It can only get better
Re: Lung Function Research - Call for volunteers
« Reply #7 on: 27 June, 2016, 11:39:39 am »
That was Aida.
Completely covered from Head to toe.
On a year out to do a masters degree which started last September.

Had a brief chat about the tandem trike 12 hour I rode and showed her a few pictures of it.
I think she might of twigged that the cycling subjects in the study are all a bit mad.

Felt a bit guilty after 15 mins twiddling without any real leg or lung discomfort.

Soon made up for that as I crept into oxygen debt and felt the burn before dissolving into a puddle of sweat.

I am sure my wight nostril is now a size larger !!!

Reg.T

  • "You don't have to go fast; you just have to go."
Re: Lung Function Research - Call for volunteers
« Reply #8 on: 21 July, 2016, 02:21:49 pm »
I was there yesterday to run through their tests. An interesting day for sure, and I'm really looking forward to getting the results sent through.
Didn't take note of many numbers as we went through, but like Assassin it was my legs that gave up (or, rather, a couple of muscles that aren't normally that exercised when riding upright) and not my breathing, although that was getting quite rapid towards the end.
Main comment was that my breathing stayed remarkably slow and deep through most of the CPET, which also helped to explain what I think they said was the highest air volume figure they'd seen through their study, peaking at 174 litres/minute.
I think they are finishing the study tomorrow.
Just turn me loose let me straddle my old saddle
Underneath the western skies

Re: Lung Function Research - Call for volunteers
« Reply #9 on: 10 October, 2016, 09:45:31 pm »
I know it's a bit late in the day but are they still looking for volunteers?

hellymedic

  • Just do it!
Re: Lung Function Research - Call for volunteers
« Reply #10 on: 11 October, 2016, 12:05:35 am »
I don't know; email them and ask...

Re: Lung Function Research - Call for volunteers
« Reply #11 on: 03 November, 2016, 10:28:12 pm »
Has anyone had any feedback from this?  I did the tests in July and Caroline said she would send the findings through but nothing so far.
The sound of one pannier flapping

Reg.T

  • "You don't have to go fast; you just have to go."
Re: Lung Function Research - Call for volunteers
« Reply #12 on: 10 November, 2016, 06:36:16 pm »
Nothing here. I did email a couple of weeks ago to enquire, but no response to that either.

ETA: Actually emailed on 2 Oct, so over 5 weeks ago.
Just turn me loose let me straddle my old saddle
Underneath the western skies

mmmmartin

  • BPB 1/1: PBP 0/1
    • FNRttC
Re: Lung Function Research - Call for volunteers
« Reply #13 on: 29 November, 2016, 06:33:52 pm »
unashamed thread revivial - did anything come through Reg? I found them efficient, might be worth a nudge or a phone call?
Besides, it wouldn't be audacious if success were guaranteed.

Re: Lung Function Research - Call for volunteers
« Reply #14 on: 01 December, 2016, 11:25:32 am »
I'm slightly miffed at the lack of response.  I have to say I found the tests one of the most unpleasant procedures I've been through in a long time - the team spent about 30 minutes trying to force tubes into my inners (one without luck despite repeated attempts).  It was beyond uncomfortable - it was actually quite painful.  The repeated electric shocks to the neck (over 50 IIRC) were also unexpected and really very unpleasant indeed.  Had I known exactly what was involved I doubt I would have volunteered.

The least we could expect is a bit of feedback.  Perhaps the project has been abandoned?
The sound of one pannier flapping

Reg.T

  • "You don't have to go fast; you just have to go."
Re: Lung Function Research - Call for volunteers
« Reply #15 on: 01 December, 2016, 07:12:45 pm »
Still waiting here.
Just turn me loose let me straddle my old saddle
Underneath the western skies

Assasin

  • It can only get better
Re: Lung Function Research - Call for volunteers
« Reply #16 on: 06 December, 2016, 12:09:36 pm »
Yes,
Me too.
I did send a reminder about the results a while back but no reply.
Just curious to see how i did in the grand scheme of things.

Re: Lung Function Research - Call for volunteers
« Reply #17 on: 14 December, 2016, 08:46:33 am »
Professor Lazarus? :o

In the absence of these results, a good lung function test is to go swimming.
Move Faster and Bake Things

Re: Lung Function Research - Call for volunteers
« Reply #18 on: 14 December, 2016, 03:20:16 pm »
I was there end of September. Caroline provided feedback as we went along. I'm not expecting anything further.

Reg.T

  • "You don't have to go fast; you just have to go."
Re: Lung Function Research - Call for volunteers
« Reply #19 on: 20 December, 2016, 03:26:57 pm »
I've just received an email from Caroline apologising for the delay in responding and with an attached document summarising the results.

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Just turn me loose let me straddle my old saddle
Underneath the western skies

mmmmartin

  • BPB 1/1: PBP 0/1
    • FNRttC
Re: Lung Function Research - Call for volunteers
« Reply #20 on: 20 December, 2016, 04:51:08 pm »
Me too. Very interesting summary - in a nutshell, older cyclists have trained their bodies whereas younger, fitter active cyclists do well in the tests because they younger. Older cyclists seem to have less flexible ribcage muscles so have trained their bodies to breath more quickly instead of, as the younger ones do, deeper.

She also said she'd underestimated the time needed to analyse the data. Also there might be further tests so we might hear from her.

I found the whole thing very interesting.
Besides, it wouldn't be audacious if success were guaranteed.

Reg.T

  • "You don't have to go fast; you just have to go."
Re: Lung Function Research - Call for volunteers
« Reply #21 on: 20 December, 2016, 06:34:45 pm »
Are people wanting to share their figures here? Mine aren't very meaningful to me in isolation...
Just turn me loose let me straddle my old saddle
Underneath the western skies

Re: Lung Function Research - Call for volunteers
« Reply #22 on: 20 December, 2016, 07:13:18 pm »
Are people wanting to share their figures here? Mine aren't very meaningful to me in isolation...

Peak W                                                                     275
End-exercise minute ventilation(L/min)                     122.6
VO2max (peak oxygen uptake)(ml/min/kg)                     50
VO2 at anaerobic threshold “ATVO2”(ml/min/kg)             34
ATVO2 as a % of VO2max(%)Predicted = 40 to 60%     68

I was 60 at the time of testing and hadn't been doing much training for the past couple of years because of injury and work.  The only figure I understand (other than the pathetic 275 watts) in the VO2Max, which interestingly is the same now as it was when last tested 7 years ago.

Thanks to Caroline and the team - obviously swamped with data!
The sound of one pannier flapping

Reg.T

  • "You don't have to go fast; you just have to go."
Re: Lung Function Research - Call for volunteers
« Reply #23 on: 20 December, 2016, 07:59:40 pm »
275 Watts not pathetic in relation to my output:

Peak W    225
End-exercise minute ventilation(L/min) 161.2
VO2max (peak oxygen uptake)(ml/min/kg)   59
VO2 at anaerobic threshold “ATVO2”(ml/min/kg)  48
ATVO2 as a % of VO2max(%)Predicted = 40 to 60%   80.2

ETA: I think my test ended earlier than it might otherwise have done due to a wrong/unaccustomed position, so a couple of leg muscles gave up rather than actually running out of puff.
Just turn me loose let me straddle my old saddle
Underneath the western skies

Assasin

  • It can only get better
Re: Lung Function Research - Call for volunteers
« Reply #24 on: 21 December, 2016, 11:55:35 am »

Peak W      275
End-exercise minute ventilation(L/min)   105.6
VO2max (peak oxygen uptake)(ml/min/kg)     36
VO2 at anaerobic threshold “ATVO2”(ml/min/kg)     26
ATVO2 as a % of VO2max(%)Predicted = 40 to 60%     72

Legs gave out before lungs - that was indicated in the study summary.
As i am quite heavy the ml/min/kg figure is lower than the other figures posted here
So not bad for the fat kid.
I agree the laid back position was a bit strange.