Yet Another Cycling Forum

General Category => The Knowledge => Health & Fitness => Topic started by: giropaul on 02 May, 2021, 12:44:27 pm

Title: Post vaccination effects
Post by: giropaul on 02 May, 2021, 12:44:27 pm
First of all, I’m totally in favour of the Covid vaccine, and if there’s a booster in the Autumn I’ll be at the front of the queue.
I had my second Pfizer jab a fortnight ago. I was fine afterwards, but I’m finding that I’m feeling a bit “ flat”, and my power figures are definitely down.
There may be no connection at all of course, but I’d be interested if anyone has had similar, and if so how quickly things returned to normal.
Distinctly preferable to getting Covid of course!
Title: Re: Post vaccination effects
Post by: woollypigs on 02 May, 2021, 01:07:24 pm
I had the first part of AZ a few weeks ago. Other than waking up in the night with a sore arm*. And then in the early afternoon I needed a good kip, just felt heavy and drained, for 4-5 hours. I haven't felt anything. Peli was under the weather for about 3 days, like she was about to come down with a cold.

*I still wake up with sore'ish arm, especially the arm on the side I was sleeping. Left overs from when I was sick some years ago, but it isn't normally that bad that I get woken up by it, but the night after the jab it was, in every joint.
Title: Re: Post vaccination effects
Post by: L CC on 02 May, 2021, 01:30:35 pm
I've been crap since I had my first dose of AZ (18th March) but it could just be that I'm crap.

I'm tired all the time and have no legs for workouts. Racing isn't as bad as workouts (implying it's at least partly psychological) but I'm not as powerful as Feb. Presumably if I can't do the workouts it's no wonder my top end power is falling off.
There is, as always, loads of other stuff going on- I'm back in the office a couple of days a week, I've had my foot 'done', I'm riding more outside, work stress which is usually acute has become a bit chronic.
Like I said, I could just be a bit crap.

Title: Re: Post vaccination effects
Post by: Pingu on 02 May, 2021, 01:48:30 pm
I had a couple of days of tiredness and achy muscles after being AZed (and confused). My jabbed arm was tender for a few days more.
Title: Re: Post vaccination effects
Post by: John Stonebridge on 02 May, 2021, 02:20:41 pm
I had AZ dose I on 3rd April.

Started feeling crap after about 48 hrs.  Developed cramp in one calf enough to make me curtail my ususal post work 5k stroll and have me genuinely hobbling about. Ive only ever had calf cramps after running and then only in two legs.  A quick butchers at the NHS website showed cramp in one leg specifically as the first listed symptom of DVT which scared the bejesus out me.  Spoke to GP who enlisted the aid of two colleagues and after about 5 hours of sending photos to and from they decided I probably didnt have a DVT.  Calf cramp subsided by about a week after first dose. 

Ive only been quantifying power output this last week with gyms returning and Im about 75% of December 2020 levels despite doing an indoor turbo session pretty much daily since start of Jan.  Perceived power while out on the road feels equivalent to around 2003 when I got back into cycling ie significantly off. 

Could be something other than the vaccine else of course (age is a strong contender!).

To be clear I dont regret getting the vaccine and I will definitely go back for 2nd dose, but Im not doubt also that the vaccine is serious shit. 
   
Title: Re: Post vaccination effects
Post by: Basil on 02 May, 2021, 02:49:51 pm
I've now had two Astrid Zen-Knickers jabs.  On both occasions it was the 3rd and 4th day after that I suffered from physical tiredness.  Not feeling ill, just exhausted and unable to keep up with Mrs B and the dog on longer walks.
I've noticed that I still get tired and go to bed much earlier in the evening than I used to. 
Title: Re: Post vaccination effects
Post by: T42 on 02 May, 2021, 03:13:40 pm
First AZ dose six weeks ago.   
J+1, J+2 bloody awful - muscular pains, muzzy, exhausted. Paracetamol helped a bit.
J+3 pain gone, still tired.
J+4 tried to ride, jacked it in after 3 km.
J+7 did a 50k, felt OK.
Fine since.
Title: Re: Post vaccination effects
Post by: FifeingEejit on 02 May, 2021, 04:08:38 pm
I was duff for a bout a week after getting my Flu jag late last year.
Then I had a week of probable Galstone issues.
Or was it the other way round? cannae mind.

Round here there was also the false start to summer, the interlude between which and real summer can mess with yir heid an aw.
Title: Re: Post vaccination effects
Post by: hellymedic on 02 May, 2021, 06:29:36 pm
I had AZ and minimal soreness at the injection site thereafter for a short while but nothing else.
D ha AZ, was unwell for 36 hours afterwards - chills & muscle aches. D has had persistent shoulder pain on the injected side, since around the time of injection, which may, or may not, be related.

I am due my second jab this week and D's is scheduled for the end of the month.
Title: Re: Post vaccination effects
Post by: LittleWheelsandBig on 02 May, 2021, 06:35:01 pm
The day after I was AZed, I spent most of it in bed and still felt a touch off-colour the following day but OK after that, though the sore arm lasted most of that week.

Still waiting for my top-up jab to come round.
Title: Re: Post vaccination effects
Post by: Graeme on 02 May, 2021, 06:40:03 pm
12 noon AZ jab. Felt fine, rode my bike a bit.

9pm same day: I suddenly started to shiver. Then was sweating buckets and physically shaking to the core with cold. A sleepless night of sweating and shivering. I dozed the following day and started to feel better by the next evening. A couple of days later I was okay.

So, I know that the vaccine is not Covid. It is designed to teach your body to protect itself against Covid. I think the speed and severity of reaction means my body recognised the shape of virus straight away and moved to kick it out the fastest way possible. My ill feelings were my body protecting itself - because I certainly didn't *catch covid* from the vaccine. I suspect I may have been asymptomatic during the last 12 months.

Taking my wife for the jab this evening. She's nervous - but would rather have the jab and any feelings of being unwell in preference to actually catching Covid. I guess if I have been asymptomatic then she will have been too, so I'm taking a couple of days to look after her just in case she gets the same reaction I did.
Title: Re: Post vaccination effects
Post by: Ian H on 02 May, 2021, 08:14:14 pm
E was quite ill for a few days after her first AZ. Her second is not for a few weeks.

I have had both Pfizers with minimal adverse effect.  Nothing more than a sore shoulder after the first, and slightly under the weather for a day or two after the second.
Title: Re: Post vaccination effects
Post by: Rod Marton on 02 May, 2021, 08:22:10 pm
Early morning jab, fine for the rest of the day except for an itchy arm (I think that microchip must have sharp edges).

Next day, feeling lethargic. Day after, still lethargic but not as much. After that, fine.

Mrs Marton had hers recently, felt rough for the rest of the day whn she had the jab, fine after that.
Title: Re: Post vaccination effects
Post by: Wowbagger on 02 May, 2021, 08:38:05 pm
I had AZ jabs on 10th Feb and 30th April. No ill-effects that I could attribute to the jab, but twice in the nights immediately following the first jab I woke up with a mild headache. Took paracetamol and went back to sleep.
Title: Re: Post vaccination effects
Post by: rafletcher on 02 May, 2021, 08:48:52 pm
My wife has had 2 x Pfizer, just a sore injection site. I’ve had 1 x AZ, slightly more sore, as in bruised feeling, upper arm for a couple of days. That’s it.
Title: Re: Post vaccination effects
Post by: neilrj on 02 May, 2021, 09:42:42 pm
My wife and I both had AZ and neither of us had any problems at all, well I imagine the slight arm soreness (of injecting anything) might bother some folk, but it's nothing to donating blood through a bloody great javelin/straw (technical term).
Title: Re: Post vaccination effects
Post by: giropaul on 03 May, 2021, 09:16:15 am
I've been crap since I had my first dose of AZ (18th March) but it could just be that I'm crap.

I'm tired all the time and have no legs for workouts. Racing isn't as bad as workouts (implying it's at least partly psychological) but I'm not as powerful as Feb. Presumably if I can't do the workouts it's no wonder my top end power is falling off.
There is, as always, loads of other stuff going on- I'm back in the office a couple of days a week, I've had my foot 'done', I'm riding more outside, work stress which is usually acute has become a bit chronic.
Like I said, I could just be a bit crap.

Many thanks for all contributions here. Fboab’s experience is especially relevant to me. I’m struggling to hold high ( for me) watt levels during structured workouts on Zwift, and when I joined a couple of experienced and sensible riders to ease back into riding with others I was in the red zone trying to hang on, despite them deliberately riding steady.
One possible curved ball is Oil Seed Rape in flower. I’m from a family with immunity issues, and so old that Oil Seed Rape wasn’t a crop during the early years when the building of immunity would have be more likely.
Title: Re: Post vaccination effects
Post by: Asterix, the former Gaul. on 03 May, 2021, 09:22:12 am
My second jab should be this week at the latest but I am struggling to get an appointment in York.

At this point re fitness, I have all my stats from Zwift and Strava (yesterday I was 2nd fastest up one of York's most challenging inclines!!) so I will let you know what happens if I get jab #2.

Sadly I just had to cancel my Raid Dolomites tour this year due to the cursed covid thing. ??? >:( :'(
Title: Re: Post vaccination effects
Post by: CrazyEnglishTriathlete on 04 May, 2021, 07:40:10 am
I felt a bit rough for 48 hours after the first AZ jab, as did Mrs CET (she even worked from home for a day, which is a rare event even during lockdown), but was OK afterwards.  Am in better shape now than I was this time last year or for about the last 5 years, which is almost certainly a coincidence, but suggests that there have been no medium term effects of the jab. 

The improvement in fitness - have just done my fastest 10k on the ergo since 2014, could be that I'm not recovering from a 300k or 400k Audax as I would normally be at this time of year.
Title: Re: Post vaccination effects
Post by: Asterix, the former Gaul. on 05 May, 2021, 06:28:58 am
Booked jab#2 for Friday after phoning surgery to find out why no contact. They said there had been supply issues and promptly offered me a choice of several slots. It’s the very end of my 12 week delay. Pfizer.
Title: Re: Post vaccination effects
Post by: nuttycyclist on 05 May, 2021, 01:28:23 pm
Side effects leaflet stated that I might feel cold.   It also stated I should read this carefully before being jabbed but I was given the leaflet as I left.

The weather changed and it did indeed get colder.  It's amazing.  Getting a vaccine caused the weather to change.


Other than that, as per any other vaccine I have had, no effect post stabbing.
Title: Re: Post vaccination effects
Post by: hellymedic on 05 May, 2021, 03:08:09 pm
2nd AZ this pm.

Will report back.
Title: Re: Post vaccination effects
Post by: ian on 05 May, 2021, 04:09:38 pm
I got the power to levitate and shoot laser beams out of my eyes. I wasn't expecting this and sadly it was temporary. For the next jab, I'm going to have my enemies and everyone who has slighted me lined up so can work through them and turn them into smouldering charcoal.
Title: Re: Post vaccination effects
Post by: Lightning Phil on 05 May, 2021, 04:10:53 pm
2nd AZ this pm.

Will report back.

Closer together than most of us. My second one will be 11 weeks after first
Title: Re: Post vaccination effects
Post by: mike on 05 May, 2021, 04:50:17 pm
Got my first AZ jab yesterday and today my hay fever seems to have cleared up.  Coincidence? Hmm.

(and very sore muscles all over, although that could also be due to a hard interval session followed by circuit training on Monday..)
Title: Re: Post vaccination effects
Post by: Graeme on 05 May, 2021, 06:06:13 pm
Taking my wife for the jab this evening. She's nervous - but would rather have the jab and any feelings of being unwell in preference to actually catching Covid. I guess if I have been asymptomatic then she will have been too, so I'm taking a couple of days to look after her just in case she gets the same reaction I did.

That went quite well. She has ME and only experienced mildly increased tiredness post-jab.
Title: Re: Post vaccination effects
Post by: hellymedic on 05 May, 2021, 07:42:04 pm
2nd AZ this pm.

Will report back.

Closer together than most of us. My second one will be 11 weeks after first

My first jab was 12/2/2021. I think that's nearly 12 weeks ago.

Still alive; awaiting a non-event but prepared for any surprise.
Title: Re: Post vaccination effects
Post by: Cudzoziemiec on 06 May, 2021, 08:01:42 am
It's amazing.  Getting a vaccine caused the weather to change.
I got the power to levitate and shoot laser beams out of my eyes. I wasn't expecting this and sadly it was temporary. For the next jab, I'm going to have my enemies and everyone who has slighted me lined up so can work through them and turn them into smouldering charcoal.
ian's vacci-powers are dramatic but on balance nutty's are more useful. A real live Weathermonger!
Title: Re: Post vaccination effects
Post by: nuttycyclist on 06 May, 2021, 09:41:47 am
It's amazing.  Getting a vaccine caused the weather to change.
I got the power to levitate and shoot laser beams out of my eyes. I wasn't expecting this and sadly it was temporary. For the next jab, I'm going to have my enemies and everyone who has slighted me lined up so can work through them and turn them into smouldering charcoal.
ian's vacci-powers are dramatic but on balance nutty's are more useful. A real live Weathermonger!

July 15th, it will be raining at my second jab location.      Location withheld for personal reasons, but I'll put my money on it and must remember to check back in here to confirm.
Title: Re: Post vaccination effects
Post by: hellymedic on 06 May, 2021, 05:26:39 pm
There's a St Swithun's roundabout in Bournemouth...

In other news, I have noted no ill-effects yet, following my 2nd AZ vaccine.
Title: Re: Post vaccination effects
Post by: Lightning Phil on 06 May, 2021, 05:52:25 pm
It's amazing.  Getting a vaccine caused the weather to change.
I got the power to levitate and shoot laser beams out of my eyes. I wasn't expecting this and sadly it was temporary. For the next jab, I'm going to have my enemies and everyone who has slighted me lined up so can work through them and turn them into smouldering charcoal.
ian's vacci-powers are dramatic but on balance nutty's are more useful. A real live Weathermonger!

July 15th, it will be raining at my second jab location.      Location withheld for personal reasons, but I'll put my money on it and must remember to check back in here to confirm.

Can you stay away from East Anglia the weekend after. I’ve got a 400 audax. Cheers
Title: Re: Post vaccination effects
Post by: nuttycyclist on 06 May, 2021, 06:11:23 pm
......
Can you stay away from East Anglia the weekend after. I’ve got a 400 audax. Cheers

I will do my best to comply with your request.
Title: Re: Post vaccination effects
Post by: Peter on 06 May, 2021, 07:29:22 pm
I am very old so have had both Pfizers now.  Absolutely no soreness or effects.  I'm sorry people are having troubles, mostly with the AZ, but it's hard to be scientific.  I did hear that increase in reactions to the AZ vaccine are proportional to obsession with cycling metrics, but I don't remember where (and I'm not blaming that on Pfizer).
Title: Re: Post vaccination effects
Post by: JStone on 06 May, 2021, 08:12:41 pm
Now double-dosed with AZ and no adverse effects from either of them.
Title: Re: Post vaccination effects
Post by: hellymedic on 07 May, 2021, 01:39:38 pm
Both D & I had feedback/satisfaction questions as we left the Mango Pharmacy (I know there's a thread in The Pub)...
Title: Re: Post vaccination effects
Post by: Deano on 07 May, 2021, 02:14:33 pm
AZ on Wednesday, nowt but a sore arm.
Title: Re: Post vaccination effects
Post by: Bledlow on 07 May, 2021, 02:23:13 pm
Two BioNTechs.

1st early January. Tender swelling at injection site. Next day felt as if I had mild flu. Lasted a couple of days.
2nd late March. Lesser version of the same.

Nothing since.
Title: Re: Post vaccination effects
Post by: Asterix, the former Gaul. on 07 May, 2021, 04:58:27 pm
Had jab#2 one hour ago - Pfizer - with mild discomfort from the stabbing. No effects so far..
Title: Re: Post vaccination effects
Post by: Asterix, the former Gaul. on 08 May, 2021, 09:15:16 am
Will give Zwift a go later and see what happens.
Title: Re: Post vaccination effects
Post by: SteveC on 08 May, 2021, 10:08:05 am
Second Pfizer. Didn't feel the jab itself (unlike the first one) but now, on the following morning, it's a bit tender.
Title: Re: Post vaccination effects
Post by: hatler on 08 May, 2021, 11:16:20 am
Mid-March AZ at 11.30am. Became shivery at 9pm and retired to bed. Got up briefly the next morning and headed back for bed, dozed on and off. Didn't eat. Felt crap, like a bad cold. Overnight got very shivery and woke suddenly at 4am thinking my hot water bottle had split. Realised it was simply sweat, but felt absolutely fine. Woke up properly at 8am and carried on as though nothing had happened. Very slightly sore arm for a couple of days after that.
Title: Re: Post vaccination effects
Post by: SteveC on 08 May, 2021, 03:14:48 pm
Second Pfizer. Didn't feel the jab itself (unlike the first one) but now, on the following morning, it's a bit tender.
Later. Feeling a bit 'meh', but can't work out whether it's the vaccine or the result of a stupid week. I enjoy doing the election, but 15 hours is a long shift, particularly when sitting in a cold village hall with the doors open, and there were too many wines when we got back home after dropping the ballot box off at the count.
A couple of paracetamol have helped.
Title: Re: Post vaccination effects
Post by: morbihan on 08 May, 2021, 03:25:43 pm
2 x Pfizer for the both of us. In the 50/60 age group.
I was fine after both, maybe a little sluggish after the second.
My partner was pretty ropey after the first shot and very sick after the second, but bounced back within 72 hours.
Small price to pay. Go get them shots!
Title: Re: Post vaccination effects
Post by: Asterix, the former Gaul. on 08 May, 2021, 06:59:30 pm
Rode a Zwift route on Thursday
Second jab Friday afternoon
Rode a similar Zwift route today

Today's ride was 90% Thursday's power.  And I feel somewhat weary afterwards which on Thursday I did not.

Otherwise I feel ok.  I'll be on Zwift again Monday all going well.
Title: Re: Post vaccination effects
Post by: giropaul on 09 May, 2021, 08:16:42 am
As I started this, I thought I should report on progress.
I did a couple of hard ( to me) structured Wattbike sessions recently- just prior to 3 weeks from Pfizer #2. I seem to be back to pre- vaccination levels.
Speaking to other friends a fair few report similar.
That’s good then, I’m not surprised that whilst the body deals with an immune response there could be an effect on more intense exercise.
Title: Re: Post vaccination effects
Post by: orienteer on 28 May, 2021, 03:39:48 pm
A week after my first Pfizer jab, back in February, I had an unusual back ache, which actually extended all the way round my waist. I also couldn't walk as fast as usual. As it didn't disappear, I eventually consulted my GP, who first gave me some exercises to try. No effect, so I was called in for a face to face consultation. By this time I was starting get pains in other joints including my hands, shoulders and neck, and each day was different, so I couldn't plan ahead.

GP diagnosed arthritis in right hip, and I had blood and urine tests and a hip scan. Tried to arrange a consultation with NHS rheumatologist - four months waiting list! At this point I decided to pay for a private consultation, which was on Thursday (27/5).

The consultant concluded it wasn't arthritis, but polymyalgia rheumatica. Great relief, as arthritis is incurable but
PR can be cured using steroids. Apparently vaccines can set this off and the consultant had had some patients following Covid vaccination.

Hope to be back on a bike soon!
Title: Re: Post vaccination effects
Post by: Lightning Phil on 28 May, 2021, 05:48:47 pm
Had second dose of AZ on Monday. On Wed I did some hard hill sessions.  Top end definitely blunted as I reached 90% max HR. I’d say it felt like rate of perceived exertion was ahead of the heart rate response.  In other words felt harder than heart rate response would indicate. More moderate longer efforts have been fine.  No side effects otherwise.
Title: Re: Post vaccination effects
Post by: zigzag on 28 May, 2021, 06:06:25 pm
had my first jab yesterday, no initial side effects, but after nine hours body temperature rose and body started to ache. no temperature today, only the jabbed arm is sore. not the thing i wanted to do, but i hope it will make traveling easier in the near future.

the doctor asked about my previous side effects before the second jab (a week ago now), and suggested to preemptively take some paracetamol for few days. which i did and was only feeling a bit off the next day.
Title: Re: Post vaccination effects
Post by: cycleman on 28 May, 2021, 06:39:02 pm
I've had both jabs now (last one 17th May)and no reactions to ethier  :)
Title: Re: Post vaccination effects
Post by: nobby on 28 May, 2021, 08:50:02 pm
I've had reactions to both my AZ jabs.
First was headaches and fevers for about three days. Second was much the same but with added random swelling of glands in neck and tiredness for a week.
I've had a blood test since the second and I am brimming over with covid antibodies.
Title: Re: Post vaccination effects
Post by: hellymedic on 28 May, 2021, 11:00:58 pm
I had no problems after my second AZ jab.
D doesn't seem to be suffering from anything after his second AZ jab.
His left shoulder pain persists but might be resolving slowly.
Title: Re: Post vaccination effects
Post by: Auntie Helen on 29 May, 2021, 07:46:40 am
I had a very sweaty night last night but feeling a bit more human now.

Today’s task is to wash all the bedding.
Title: Re: Post vaccination effects
Post by: rogerzilla on 29 May, 2021, 08:12:00 am
There's a lot of discussion.on this in the P&OBI "when will you get vaccinated?" thread too.
Title: Re: Post vaccination effects
Post by: rogerzilla on 29 May, 2021, 08:13:09 am
It's amazing.  Getting a vaccine caused the weather to change.
I got the power to levitate and shoot laser beams out of my eyes. I wasn't expecting this and sadly it was temporary. For the next jab, I'm going to have my enemies and everyone who has slighted me lined up so can work through them and turn them into smouldering charcoal.
ian's vacci-powers are dramatic but on balance nutty's are more useful. A real live Weathermonger!

July 15th, it will be raining at my second jab location.      Location withheld for personal reasons, but I'll put my money on it and must remember to check back in here to confirm.
You are Karen from Mean Girls and ICMFP.
Title: Re: Post vaccination effects
Post by: Wobbly John on 29 May, 2021, 03:15:46 pm
No effects from first jab back in March, but have had 8 hours of feeling too tired to do much (comparitively - 3 lots of washing, lawns cut, floors cleaned, half an hour on the allotment, etc...)
Title: Re: Post vaccination effects
Post by: Wowbagger on 30 May, 2021, 09:42:31 pm
I just had a long natter to my pal Mel (73-ish), whom I haven't seen for quite a while. He told me that his first Pfizer jab started his asthma off. The second made it much, much worse, to the point that he was avoiding going to the loo for as long as possible as climbing the stairs caused breathing difficulties. It's over a month since his second dose and he's been to see his doctor, who has prescribed steroids etc. His daughter-in-law is a consultant specialising in respiratory stuff, so he's getting decent advice, and he thinks things are gradually improving.
Title: Re: Post vaccination effects
Post by: spesh on 02 June, 2021, 01:19:25 pm
It's amazing.  Getting a vaccine caused the weather to change.
I got the power to levitate and shoot laser beams out of my eyes. I wasn't expecting this and sadly it was temporary. For the next jab, I'm going to have my enemies and everyone who has slighted me lined up so can work through them and turn them into smouldering charcoal.
ian's vacci-powers are dramatic but on balance nutty's are more useful. A real live Weathermonger!

July 15th, it will be raining at my second jab location.      Location withheld for personal reasons, but I'll put my money on it and must remember to check back in here to confirm.
You are Karen from Mean Girls and ICMFP.

That, or he's been turned into a Quasi Supernormal Incremental Precipitation Inducer, per the H2G2 minor character Rob McKenna (https://en.wikipedia.org/wiki/List_of_The_Hitchhiker%27s_Guide_to_the_Galaxy_characters#Rob_McKenna). ;)


EDITED TO ADD:

Oddly enough, the weather round my way was lovely first thing, and was still nice when I got my 2nd jab, but it clouded over at lunchtime and now it's raining.


<Exits stage left, muttering "correlation is not causation...">
Title: Re: Post vaccination effects
Post by: hellymedic on 02 June, 2021, 05:19:44 pm
D had his 2nd jab a week ago, I observed some bruising at the injection site today. I don't think he's had anything else.
Title: Re: Post vaccination effects
Post by: campagman on 02 June, 2021, 08:43:07 pm
had my 2nd jab this am. Nothing to report. I did feel a little tiredness when doing some exercise this eve. though.
Title: Re: Post vaccination effects
Post by: graculus on 03 June, 2021, 11:30:25 am
2nd jab (AZ) yesterday first thing. No effects apart from slightly sore arm overnight and at present (as opposed to the first which had me in bed with the shivers by the evening).
Title: Re: Post vaccination effects
Post by: hellymedic on 03 June, 2021, 01:35:07 pm
2nd jab (AZ) yesterday first thing. No effects apart from slightly sore arm overnight and at present (as opposed to the first which had me in bed with the shivers by the evening).

Similar to D then.
Title: Re: Post vaccination effects
Post by: Croft on 07 June, 2021, 12:05:38 pm
Just to add to our collection of anecData. I've had two AZ Jabs 12 weeks apart. As far as I am aware, I've not had Covid.

First one 4pm, felt OK going to bed that evening, but soon developed fever, aches and mild delirium through the night with little sleep. Completely wiped out the following day with aches and fever and bed bound. Moderate tenderness around my jabbed arm. Second day was still very wiped out but could get out of bed. Took about 6 days to get back to normal.

Second jab two days ago also at 4pm. Recognised a similar but milder 'heady' feeling by early evening. Took precautionary paracetamol and slept through the night. Next day a little tired but started OK. But by 11am aches and fatigue started again and retired to spend most of day in bed. Similar tenderness around jab site. Next day, still a little tired and 'heady', but far less severe, probably about the same as 'day 3' after first jab.

So overall, similar significant reactions to both jabs, but second one not quite as bad as first.
Title: Re: Post vaccination effects
Post by: T42 on 18 June, 2021, 08:28:37 am
2nd AZ shot yesterday. No noticeable after-effects - which could mean of course that our immune systems recognized the adenovirus shell around the mRNA DNA and destroyed the vaccine before it could start work...

Somebody please refute this.
Title: Re: Post vaccination effects
Post by: ian on 18 June, 2021, 10:34:17 am
2nd AZ shot yesterday. No noticeable after-effects - which could mean of course that our immune systems recognized the adenovirus shell around the mRNA and destroyed the vaccine before it could start work...

Somebody please refute this.

While possible, there has been no evidence in any of the trials to date that this is a significant effect with the current two-shot regimen. There will be some immune clearance of vector, but only a modest level needs to find its way into dendritic cells to trigger a significant immune response, both the adenovirus vectored and encapsulated mRNA vaccines trigger an intrinsic adjuvant effect through nucleic acid sensing mechanisms – these basically amp up the immune system by releasing interferon and several cytokines – in the dendritic cells, which kicks off a strong response (in part this is probably why these vaccines have more notable side-effects).
Title: Re: Post vaccination effects
Post by: T42 on 18 June, 2021, 11:24:47 am
2nd AZ shot yesterday. No noticeable after-effects - which could mean of course that our immune systems recognized the adenovirus shell around the mRNA and destroyed the vaccine before it could start work...

Somebody please refute this.

While possible, there has been no evidence in any of the trials to date that this is a significant effect with the current two-shot regimen. There will be some immune clearance of vector, but only a modest level needs to find its way into dendritic cells to trigger a significant immune response, both the adenovirus vectored and encapsulated mRNA vaccines trigger an intrinsic adjuvant effect through nucleic acid sensing mechanisms – these basically amp up the immune system by releasing interferon and several cytokines – in the dendritic cells, which kicks off a strong response (in part this is probably why these vaccines have more notable side-effects).

Nice to know, thanks, Ian.

Of course I should have written DNA, not mRNA.
Title: Re: Post vaccination effects
Post by: rogerzilla on 18 June, 2021, 11:50:53 am
No effects from second jab, same as first.
Title: Re: Post vaccination effects
Post by: Jakob on 07 July, 2021, 08:01:41 am
Just got my 2nd short (Moderna, first was AZ) and it's been prolonged feverish/brain fog. Not enough to sleep, but enough to not being able to focus on anything. Hopefully it'll be gone by tomorrow.
Title: Re: Post vaccination effects
Post by: nuttycyclist on 07 July, 2021, 05:34:45 pm
I had second jab a couple of weeks ago.

Other than sweating buckets in the motorbike gear waiting in the hot sun in the car park for the 15 minutes before I was allowed to "drive" (I didn't want to get pernickety as to whether I was driving or riding), no effects from either.
Title: Re: Post vaccination effects
Post by: Jakob on 07 July, 2021, 07:14:42 pm
Full on flu-symptoms over night. That wasn't fun. Much better now.
Title: Re: Post vaccination effects
Post by: citoyen on 08 July, 2021, 11:42:57 am
First one 4pm, felt OK going to bed that evening, but soon developed fever, aches and mild delirium through the night with little sleep. Completely wiped out the following day with aches and fever and bed bound. Moderate tenderness around my jabbed arm. Second day was still very wiped out but could get out of bed. Took about 6 days to get back to normal.

Second jab two days ago also at 4pm. Recognised a similar but milder 'heady' feeling by early evening. Took precautionary paracetamol and slept through the night. Next day a little tired but started OK. But by 11am aches and fatigue started again and retired to spend most of day in bed. Similar tenderness around jab site. Next day, still a little tired and 'heady', but far less severe, probably about the same as 'day 3' after first jab.

So overall, similar significant reactions to both jabs, but second one not quite as bad as first.

This is almost identical to my experience (also with AZ). I had the first jab about 3pm on a Tuesday and the effects didn't really start to kick in until the following morning, but then they were pretty bad and I was pretty much incapacitated for the whole of that Wednesday. Wasn't back to normal until around Thursday lunchtime, but still felt a bit wiped out for a few days after.

Had the second jab first thing yesterday morning (11 weeks after the first). The effects started to kick in around 7pm - and like you, I recognised what was happening so did the precautionary paracetamol thing. I was in bed by 8.30pm.

Still feeling rough today but not nearly as bad as after the first jab.