The Bow flyover is an absolute disgrace for pedestrians and cyclists, as Diamondgeezer says.
As a for instance, a few weeks ago I decided to visit the Olympics viewing tower, which is near Pudding Mill on the DLR. DLR was shut, so replacement bus from Stratford Tube station. Bus drops us on south side of Bow flyover, with no directiosn on how to reach the DLR station. We were left to cross four lanes of fast moving traffic with no pedestrian crossings or lights - with a wheelchair. Totally scary situation - it only took one driver swinging off the roundabout at speed and we would have been run down. As DG says: "I give thanks that I'm not elderly, because I probably wouldn't dare risk it, and were I in a wheelchair I'd have absolutely no hope whatsoever."
Another for instance - on every cycle journey along the Lee you used to have to get off the towpath and cross those same lanes of traffic. There is a new floating towpath, I haven't used it yet.
And just read that ridiculous response from Boris - basically "F U pedestrians. Take your chances". Well Boris - I didn;t vote for you, and will certainly never, ever vote for you in the future if that's your attitude.