Highest top has been 48:11 on 26 inch wheels, with 52:12 on 700c a close contender. Neitehr have ever seen much use - changing up at around 105rpm cadence on descents means that I am probably going 'fast enoughTM' long before I am in danger of really needing that gear.
On last night's, admittedly spinny, excursion I only used the 39 ring, don't think I used the 12 or even 13 cogs and my top speed was 26.5mph. Really don't think I need 50:11, even if I could push it. I've always been impressed in the TdF time trials when they're pushing 53 or 54 11 on the flat.