I should note that the only time I've had mudguard trouble on the Streetmachine (that wasn't caused by a train) was after about 4 hours of riding on Dutch cyclepaths. I had to stop and apply nylocks.
Cos you of course carry spare Nylocs...
To be fair, only two (M5 and M6, which covers all the things that use nuts on that bike). But I was riding a loaded Streetmachine through .nl, I could have been carrying half the Park Tools catalogue and not noticed the extra weight.
To date there have been four occasions when I've needed a spare nut:
1) Rack bolt stripped the braze-on threads on my second ever cycle-camping trip, which involved a lot of what would these days be described as 'gravel' riding, with cheap (read: heavy) kit. I nicked a nut and bolt from a less critical bit of the rack and bodged it till I got to Bristol, from whence there were trains.
2) Basil had some sort of saddlebag problem on some exploratory ride in the Lichfield direction, and I helpfully pointed out that he could steal one from somewhere else on the bike.
(This was the point where someone on the forum had a cleat bolt incident, and I added a stratgic selection of nuts, bolts and washers to my touring kit.)
3) One of Roger's comedy friends on a FNRttS suffered a catastrophic failure of the brake lever pivot. Having previously awed him with my level of preparedness in bringing a spanner or something, he was practically floored by me digging out a M5 nut, bolt and washer that did the job perfectly. He's probably still riding around with it.
4) The afore-mentioned .nl trip, where one of the rear mudguard bolts shook loose (I think shortly after leaving the ferry, judging by the noise it was making - I'd assumed it was just some weird suspension resonance thing like you sometimes get on gravel at speed).
I think I donated a cleat bolt to cycleman at one point. And I've certainly used the spare chain link that also lives in that kit
[1]. And, weirdly, the pair of cable end ferrules that I put in there as a one-off because reasons and forgot to remove actually came in useful for a friend's kid's bike on which the fraying front gear cable was stabbing them in the leg. The disc brake pads and spare springamathing remain unused, as do the spare chainring bolts (though only just - I caught it just in time). I've also got an assortment of glasses screws in the little sewing kit I carry when touring, which should save an hour or two next time I ride across Wales
[2] with Wowbagger.
Anyway, it's that weight/bulk to how much of a problem it might solve ratio thing. Nuts and bolts and quick links and the like score very highly on account of extreme smallth.
[1] My own mechanicals are overwhelmingly chain-related.
[2] If Wales is involved, I add an extra spare gear cable, but that's getting rather off topic.