I recently restored some STi front caps from a pair of Tiagra levers (4400) that are obsolete.
Rub down, 2 coats of etch primer, several coats of grey metallic, several coats of lacquer. All acrylic from Hycote as matching brands is the best way to eliminate any chance of reaction.
All done quite quickly but dried off after every coat by a 2kw fan heater. A method I've used before for both plastic and metal components, place the painted parts in the vicinity of the heater, not on it or directly in the air stream.
Using solvent based paint obviously means risking the paint melting the plastic but you need to be pretty ham fisted for this to happen. As long as your first coats are delivered from a distance - say 45-60cm - it's unlikely the surface will get 'wet' enough for a serious reaction. Warming your aerosols first helps too.