I did monovision for 5-7 years, once presbyopia finally showed up at about age 50.
But, after changing optometrists, I've been in distance-preferred only, with readers. Soft lenses, some astigmatism.
Because? Well, after the monovision, my eyes had gotten to the point were they weren't working together well. May have been happening for a while, but it took going to someone who checked how my eyes were working together, versus how each eye did on its own. She found that my depth perception had dropped off, and that my eyes weren't looking at the same level (left eye is looking a bit above the right one, if that makes sense).
I liked monovision while I was doing it; however, wish I'd stopped just a bit earlier.
Readers are a hassle. Inexpensive wrap-around safety glasses, with a "reader" section, in clear or tint work well for cycling, however.
Seeing a doctor who will check to find out which eye is dominant, how they work together, etc. is a good idea. Many don't check for this.