Having seen male dogs *freak out* when there's a bitch in heat nearby, I wouldn't hesitate to do it.
We only went through one heat cycle with Hana and having to be paranoid with regards to intact males was not fun.
Ok, so our neighbours French bulldog, who was Hana's best friend, was fun, as he clearly had no idea how to react to his hormones.
Also saw one lady getting dragged half across the street by her rather large pitbull before she managed to get it under a resemblance of control.