Funnily enough, I have just had this conversation at work. The old stuff used to knock me out quite effectively and if alcohol was foolishly taken concurrently, actually rendered me almost comatose. (i terrified a friend once when i was 15 or so. She really thought I was dead and called an ambulance). The modern ones seem to have a less drastic effect. However, my energy levels still seem to be lowered once I start taking the neoclarityn I am prescribed which I believe is a brand of loratidine. I decided to stop taking it for a couple of days, I was feeling so sluggish and I do feel much better, energy wise, though my eyes and nose have been streaming and itching like mad. I always get a nasty wheeze with my hay fever, too, not full blown asthma, but it made the little climb up Greenwich Park on the singlespeed tougher than usual this morning.