My actual route was from the north, through Clifton Hampden, Long Wittenham, North & South Moulsford and Blewbury, heading for West Ilsley, Lilley, and Peasemore, all very nice roads except for that dratted half mile section.
I've ridden (mostly up for some reason) Streatley Hill enough times for an entire Hill Climb event, and up or down the road from Farnborough (Oxon) fairly often too. The Streatley to Wantage observation was to point out the complete dearth of north-south routes between the two places. I did once ride from Compton to Blewbury, and might do again under very dry conditions but last Sunday wasn't very dry. The good news was that I beat the rain by 10 minutes, so the A34 was free from spray.