Yet Another Cycling Forum

General Category => The Knowledge => Health & Fitness => Topic started by: quixoticgeek on 26 September, 2021, 10:36:11 pm

Title: LFT's for other bugs
Post by: quixoticgeek on 26 September, 2021, 10:36:11 pm

LFT's for the current plague are pretty much ubiquitous now. Which got me thinking, do they exist for other common illnesses. Like flu ?

J
Title: Re: LFT's for other bugs
Post by: Kim on 26 September, 2021, 11:15:16 pm
I believe the lateral flow principle forms the basis of all sorts of laboratory assays, including identifying diseases. Often these use low levels of fluorescence and electronic sensors, rather than something that can be seen by the naked eye.

The one we're most familiar with is the hCG pregnancy test...
Title: Re: LFT's for other bugs
Post by: quixoticgeek on 26 September, 2021, 11:16:43 pm
I believe the lateral flow principle forms the basis of all sorts of laboratory assays, including identifying diseases. Often these use low levels of fluorescence and electronic sensors, rather than something that can be seen by the naked eye.

The one we're most familiar with is the hCG pregnancy test...

That's a parasite... not an infection :p

J
Title: Re: LFT's for other bugs
Post by: ian on 27 September, 2021, 09:58:43 am
Yes, they are. Techniques like Enzyme-Linked Immunosorbent Assays (ELISA) are very common, the LFT is just a 'consumer' variant that can be read by eye. They're used for all kinds of things (from drugs test, environmental pollutants to Ebola). They've traditionally not been used so much in clinical contexts though, mostly due to the regulatory burden of debuting a clinical test (it's cheaper and easier to do it in a lab).
Title: Re: LFT's for other bugs
Post by: Regulator on 27 September, 2021, 10:54:50 am

LFT's for the current plague are pretty much ubiquitous now. Which got me thinking, do they exist for other common illnesses. Like flu ?

J


There are a range of LFTs out there.  As Kim says, the most ubiquitous one is the pregnancy test (developed by Paul Davis in the 1980s).   

Paul Davis co-founded Mologic (https://mologic.co.uk/) in the early 2000s.  Mologic has developed a range of LFTs, including for monitoring HIV.  It's focus is on developing countries and it has recently been taken over by George Soros' Economic Development Fund and the Gates Foundation (https://mologic.co.uk/mologic-to-become-a-social-enterprise-after-acquisition-by-social-impact-funders-and-investors/) (cue all sorts of right wing conspiracy theories).
Title: Re: LFT's for other bugs
Post by: ian on 27 September, 2021, 11:04:23 am
They've come into their own in places where clinical labs are uncommon or nonexistent (hence the use for diagnosing Ebola and HIV in Africa).
Title: Re: LFT's for other bugs
Post by: IanDG on 03 November, 2021, 05:12:00 pm
When I were in a lab we used them for malaria, RSV and c-diff
Title: Re: LFT's for other bugs
Post by: quixoticgeek on 08 January, 2023, 11:16:33 pm


https://www.alcoline.nl/product/fluorecare-sars-cov-2-influenza-a-b-en-rsv-antigen-combo-test-kits-1-test-kit/

Page is In Dutch, but Google translate work quite well

LFT for COVID, Flu A, Flu B, and RSV.

Am pondering getting a couple for stock for next time I'm not feeling great.

J
Title: Re: LFT's for other bugs
Post by: hellymedic on 09 January, 2023, 11:46:31 pm
https://www.alcoline.nl/product/fluorecare-sars-cov-2-influenza-a-b-en-rsv-antigen-combo-test-kits-1-test-kit/
Page is In Dutch, but Google translate work quite well
LFT for COVID, Flu A, Flu B, and RSV.
Am pondering getting a couple for stock for next time I'm not feeling great.
J

I'd be tempted if I were prone to Lurgies and mixing with the General Public.

As I'm mostly a Masked Hermit, I won't bother.
Title: Re: LFT's for other bugs
Post by: barakta on 10 January, 2023, 12:46:43 pm
I could see those being useful for some at-risk people or care home staff, but no one will use them cos they don't have sick leave or suitable staff cover, so instead just put care home residents/disabled people at risk instead....
Title: Re: LFT's for other bugs
Post by: hellymedic on 10 January, 2023, 05:05:13 pm
I could see those being useful for some at-risk people or care home staff, but no one will use them cos they don't have sick leave or suitable staff cover, so instead just put care home residents/disabled people at risk instead....

Wouldn't it be great to screen healthcare staff weekly & pay them adequately to stay home if positive?
Title: Re: LFT's for other bugs
Post by: barakta on 10 January, 2023, 07:23:06 pm
Yes, but that would require changing the presenteeism culture of 'work no matter how sick you are' and indeed could cause issues where if you are sick but not screening positive for one of these, then you're not really sick.
Title: Re: LFT's for other bugs
Post by: Pickled Onion on 10 January, 2023, 07:40:39 pm
I believe the lateral flow principle forms the basis of all sorts of laboratory assays, including identifying diseases. Often these use low levels of fluorescence and electronic sensors, rather than something that can be seen by the naked eye.

The one we're most familiar with is the hCG pregnancy test...

That's a parasite... not an infection :p

J

 ;D ;D ;D