One benefit of long-time cat ownership is that I have ninja mouse catching reflexes. I grab them by the tail, hoist them up, and if they're looking bitey, spin them a little. Once you have a good hold of their tail, there's not a lot they can do but hang there and admit defeat. Then I take them outside, release them somewhere where the cats can't possibly find them.
Then about twenty minutes later I do it all again with what looks suspiciously like the very same mouse.