We're getting off the point a bit here but it's all interesting stuff.
I hear what people say about the Schwalbe One but you will have gathered I have a somewhat jaundiced opinion of Schwalbe.
Citing examples of tyres used in speed record attempts where the vehicle is a faired recumbent and the road is billiard table smooth with no corners doesn't have much relevance in the real world of everyday cycling. Alex Moulton has a tyre specially made by Wolber to fit his small wheel creations which IIRC he claimed had the lowest rolling resistance of any tyre available at the time - on a drum tester. When was the last time anyone saw a 17" wheel Moulton?
I don't have any "science" to back up any of my assertions, it's my opinion based on my own experience. Many disagree, clearly, so be it. But, FWIW, for a couple of years I rode a recumbent trike, nothing else, and tadpole riders discuss tyres constantly. It's because there's 50% more rolling resistance. Like others, I tried a variety of Schwalbe tyres - they actually make one specifically for trikes - and nothing came close to a set of cheap Kendas that I nicked off my Dahon folder.
BTW I notice the Schwalbe One is heavily discounted in many stores.
The trouble is there's a dearth of real world research when it comes to bicycle tyres, and a lot of often confusing anecdotal lore which I admit I am contributing to...
The handling implications of changing wheel sizes isn't a big deal if we're comparing narrow 700c and wide 650b as you end up with negligible drop. Going 700c to 26" would obviously lower the BB and the trail, other things being equal but if you change tyre sizes as well as the wheel size... the results, I'd suggest, aren't always predictable. I'd be interested in hearing more about Soujournermike's experience with the LHT.
Samuel D - couldn't agree more with the appalling state of modern car design and it's an interesting point you make about aesthetics. I totally disagree with Kim, I find the effect of modern vehicles on the landscape/streetscape in this country quite offensive. How often have you been to a charming rural village the appearance of which is completely ruined by godawful looking modern machinery parked everywhere. Just to get back on track though, if all I was bothered about was a bike to trundle up and down towpaths then fine who cares what it looks like but I still like to pretend I am a racing cyclist again it's pathetic really.
I'm going off the Straggler BTW, the geometry's all wrong for me. The Condor Fratello disc currently has my attention even though the tt isn't quite level those bikes really do look classy. Just my opinion, of course...