Situation is much improved after a week off the MTB - however, as hinted above, trike also not ideal. More tweaking needed.
It's probably true to say that while hardshell seats can be horribly uncomfortable unless pretty much spot-on, mesh seats are relatively forgiving (except of sturdy thighs), but a lot harder to get adjusted right. Every time you adjust a strap, it affects the tension on the adjacent ones...
I'd avoid closed cell foam, though, at least as an upper layer. While it doesn't absorb water, it doesn't allow it through either. Mesh seats breathe pretty well, and you really want to preserve that property if possible. Closed cell foam means all the clothing on your back gets soaking wet as you ride along, regardless of temperature. It's also an insulator, so you tend to need fewer layers. If the ambient temperature is anything other than 'hot', this means rapid cooling as soon as you stop riding.