With all these devices, there are a few approaches to using them to navigate a pre-defined route, most of which involve you sitting down at the computer and doing your homework properly before the ride. Where they tend to go wrong for cyclists is if you allow the unit to make too many routing decisions (using it like a car satnav), or if you download a random GPX file from the internet and blindly trust it to be accurate and/or compatible with your maps/device.
The sweet spot for reliability of the tech is uploading a Track to the device, which displays as a line on the map (actually, you don't even need a map), and you simply follow it. You get a map that's backlit, waterproof, won't tear in the wind and never needs to be flipped over. The problem with that is - like a routesheet - it doesn't guarantee that you're paying attention. Unlike a routesheet, it's a lot more useful when you do go off-route.
The sweet spot for tired/stupid/distracted/visually challenged riders is auto-routing with full turn-by turn (arrows and warning beeps) navigation. There's something of a black art to crafting a Route that follows the route you actually want it to, and glitches in the map data can cause unexpected behaviour. You can't avoid a learning curve if you want to use it like that, unless you're happy to tell it a destination and follow it blindly as it takes you down the local motorway-in-all-but-name or boggy Sustrans path.
They all do pretty much the same thing as regards data logging, though eTrexes are more fool-proof (they're always recording), and Edges allow you do do more performance-related stuff on the unit. If you're just putting your track log into Strava or a mapping tool to see how fast you were or where you actually went, there's nothing in it.
The eTrex series in particular shows its heritage as a tool to be used alongside a map and compass: While it has some modern car satnav-type features, the UI paradigm is still the sort of thing you'd expect to find in a 1990s cockpit or bridge. The Edge series is very much a performance cycling-oriented device, so many of the general-purpose navigation features have been sidelined in favour of training aids and analysis.