Since I reached 50 never a year goes by without such an activity and/or having something inserted in me.
My recent Over-50s NHS Bowel-Screening even beat my Prostate exams on the scale of - 1 to "Errr..Doctor...I think that's far enough".*
In case you were wondering it's a fiber-optic camera, equipped with a grabber and CO2 inflation nozzles.
They inflate you with CO2 as they go along and it is fairly unpleasant because it actually does feel like you may explode.
None of this embarrassment or discomfort would, I am certain, be anywhere near as bad as the long-term effects, and treatment of, undiscovered cancer up the Poo-pipe.
It's a very small price to pay to either get the all-clear or discover it early in my opinion.
* 'I'm sure he was wearing a wrist watch before he started'