Oh look, I appear to have wandered in here again.
Well, for those readers curious to know what happens when you are defrosting a piece of plastic-bagged frozen rolled brisket, using the OVEN defrost setting, and at some indeterminate point before completion of said activity turn the oven to cook (160 fan) by mistake and leave it there for ...ooooo a good while.....I can tell you that you can recover from it by cooking a further many hours and you can hardly taste the plastic.